熒光素及其衍生物是一類重要的氧雜蒽類熒光染料,它們具有優(yōu)良的光譜性質(zhì),一直是化學(xué)及生物分析領(lǐng)域中的研究熱點(diǎn)。隨著生命科學(xué)的不斷發(fā)展,大量以熒光素為核心的熒光探針已在蛋白質(zhì)、核酸、細(xì)胞檢測及免疫分析等方面發(fā)揮了舉足輕重的作用[1]。百靈威作為專業(yè)試劑供應(yīng)商,供應(yīng)40余種熒光素染料。
- 光穩(wěn)定性好
- 較長的激發(fā)和發(fā)射波長
- 較高的熒光量子產(chǎn)率
產(chǎn)品編號
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英文名稱
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中文名稱
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CAS
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包裝規(guī)格
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299867
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5-Aminofluorescein, 95%
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5-氨基熒光素, 95%
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3326-34-9
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250 mg
1 g
5 g
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255493
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Fluorescein isothiocyanate isomer I, 95%
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異硫氰酸熒光素異構(gòu)體I, 95%
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3326-32-7
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250 mg
1 g
5 g
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223219
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2',7'-Dichlorofluorescein
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2',7'-二氯熒光素
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76-54-0
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1 g
5 g
25 g
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圖 1: Fluorescent images from two glioblastoma patients. A, fluorescence from the tumor tissue demonstrating a distinct penetration of (299867)5-aminofluorescein (AFL)-human serum albumin (HSA) at the fenestrated tumor vessels as a result of the disrupted blood- brain barrier (Patient 3). B, yellow- green fluorescent glioblastoma at the cortical surface in Patient 8. Sequence of residual fluorescence in the same patient at the bottom of the tumor resection cavity after microsurgical tumor removal[1].
圖 2: Optic Nerve Head and Surrounding Region in the Right Eye. A, The fluorescein(916551) angiographic image. B, The optical coherence tomography angiography image of the same region in which the radial peripapillary capillary network is readily visible[2].
References
[1] Kremer P, Fardanesh M, Ding R, et al. Intraoperative fluorescence staining of malignant brain tumors using 5-aminofluorescein-labeled albumin.[J]. Neurosurgery, 2009, 64(3):53-61.
[2] Spaide R F, Klancnik J M, Cooney M J. Retinal Vascular Layers Imaged by Fluorescein Angiography and Optical Coherence Tomography Angiography[J]. Jama Ophthalmology, 2015, 133(1):45-50.
產(chǎn)品編號
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英文名稱
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中文名稱
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CAS
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包裝規(guī)格
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258764
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5(6)-Carboxyfluorescein, 97%
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5(6)-羧基熒光素, 97%
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72088-94-9
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500 mg
1 g
5 g
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186468
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5(6)-Carboxyfluorescein N-hydroxysuccinimide ester, 90%
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5(6)-羧基熒光素(N-羥基琥珀酰亞胺)酯, 90%
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117548-22-8
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25 mg
100 mg
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404608
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2',7'-Dichlorofluorescein 3',6'-diacetate, 96%
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2',7'-二氯熒光素 3',6'-二乙酸酯, 96%
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2044-85-1
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250 mg
1 g
5 g
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916551
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Fluorescein, 95%
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熒光素, 95%
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2321-07-5
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25 g
100 g
500 g
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945793
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Fluoresein-PEG-Fluoresein, average M.W. 10,000
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熒光素-PEG-熒光素, 平均分子量 10,000
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N/A
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1 g
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184636
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5-?(Iodoacetamido)?fluorescein, 95%
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5-碘乙酰氨基熒光素, 95%
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63368-54-7
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25 mg
100 mg
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